Characterization of the promoter for the human factor I (C3b/C4b inactivator) gene

  • 4.25 MB
  • English
National Library of Canada , Ottawa
SeriesCanadian theses = -- Thèses canadiennes
The Physical Object
Pagination2 microfiches : negative. --
ID Numbers
Open LibraryOL18812179M
ISBN 100612340775

Database searches. Human PANK2 genomic organization was obtained from the UCSC Human Genome Browser (Kent et al., ) and sequence comparisons were performed using the ECR Browser (Ovcharenko et al., ), Mulan (Ovcharenko et al., ) and ClustalW2 (Larkin et al., ).The transcription factor binding sites in the promoter region Cited by: 6.

To study the relationship between the promoter element in the PPRs and the transcriptional level of genes, we associated the PPRs with the expression profiles obtained by iAFLP.

iAFLP is an RT-PCR-mediated gene quantification method (Kato ; Kawamoto et al. ) and now expression levels among 30 kinds of human tissues are available for Cited by: 1. Introduction. The S proteins are a family of low molecular weight (9–11 kDa) calcium-binding proteins (Moore,Isobe et al.,Isobe and Okuyama, ).SA10, also known as p11 or calpactin I light chain, is a distinct member of the S family in that the EF-hands carry mutations that limit its ability to bind calcium (Gerke and Weber, ).

p11 is the Cited by: Characterization of the Cloned Promoter of the Human Initiation Factor 4AI Gene is ubiquitously expressed in eucaryotic cells.

We characterized the eIF-4AI gene promoter cloned from human fibroblasts.

Description Characterization of the promoter for the human factor I (C3b/C4b inactivator) gene FB2

The minimal promoter, localized to a region in the 5′-noncoding region adjacent to the first exon, consisted of approximately base Cited by: 2. THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol.No. 1, Issue of January 5, pp.Printed in U.S.A.

Characterization of the Promoter Region of the Human Transforming Growth Factor-P1 Gene* (Received for publication, June 7, ) Seong-Jin Kim#, Adam Glicks, Michael B. Sporn, and Anita B. Roberts From the Laboratory of. The 5'-end of the human transforming growth factor-beta 1 gene (TGF-beta 1) was Characterization of the promoter for the human factor I book from a human leukocyte genomic DNA library.

Analysis of the transcriptional start sites of human TGF-beta 1 mRNAs by S1 mapping and primer extension revealed two major start sites nucleotides from one another; several minor sites were also identified.

The promoter region of the human aldose reductase gene has been identified upstream of the translation start ATG codon. The promoter contains a TATA box, a. Nitrosative stress, a potential factor in human neu-rodegeneration, stimulated Sp1 expression and human p11 promoter activity, at least in part, through a Sp1-binding site.

Human TSPY is a candidate oncogene and is supposed to function as a proliferation factor during spermatogenesis. It is the only mammalian protein-coding gene known to be organized as a tandem repeat gene family.

It is expressed at highest level in spermatogonia and to a lower amount in primary spermatocytes. To characterize the human TSPY promoter Cited by: 7.

Abstract. Since the initiation of the Human Genome Project (1, 2, 3), project originators have envisioned a need for the development of computer software programs to analyze and annotate the massive amount of sequence data expected to be produced as a result of sequencing efforts ().Efforts directed toward this goal include the development of computer software for gene and Cited by: Functional characterization of the human SOX3 promoter: identification of transcription factors implicated in basal promoter activity Natasa Kovacevic Grujicic, Marija Mojsin, Aleksandar Krstic, Milena Stevanovic* Institute of Molecular Genetics and Genetic Engineering, Vojvode Stepe a, P.O.

Details Characterization of the promoter for the human factor I (C3b/C4b inactivator) gene PDF

Belgrade, Serbia and Montenegro. (A) Genomic footprinting of the FMR1 gene promoter. The region shown was analyzed with primer set X (primers X1, X2 and X3, Table 2) to reveal upper strand sequences from nt − to −35 relative to the major transcription initiation 1–4, LM-PCR of DNA treated with standard Maxam-Gilbert cleavage reactions; lanes 5 LM-PCR of normal Cited by: CHARACTERIZATION AND CLONING OF THE HUMAN PERLECAN PROMOTER REGION by Matthew T.

Richards Table A.3 Genomatix Analysis of the Human Perlecan Promoter Region from Figure Human Pln promoter region with transcription factor binding sites. In this study we have cloned and characterized the human GFI1 promoter. The nucleotide sequence of the promoter region is GC-rich and does not contain a typical TATA or CAAT box.

Download Characterization of the promoter for the human factor I (C3b/C4b inactivator) gene EPUB

Several Sp1 sites are present and computer predictions indicate that either of the two Sp1 sites might serve as the sites for transcription by: In the present study, we chose to undertake a functional characterization of the human GPV gene promoter for the following reasons.

First, GPV associates in stoichiometry with GPIb-IX and is absent or found at low levels in most Bernard-Soulier patients, suggesting a possible coordinated control of by: The Human Factor (novel), a novel by Graham Greene.

The Human Factor: Revolutionizing the Way We Live with Technology, a nonfiction book by Kim Vicente. The Human Factor: Inside the CIA's Dysfunctional Intelligence Culture, a nonfiction book by Ishmael Jones.

The Human Factor (album) or the title song, by Metal Church, The Human Factor by Graham Greene is a novel about Maurice Castle. He is 62 years and does office work for a British intelligence agency. He is married to. The cotton (+)- δ -cadinene synthase (CAD1), a sesquiterpene cyclase, catalyzes a branch-point step leading to biosynthesis of sesquiterpene phytoalexins, including gossypol.

CAD1-A is a member of CAD1 gene family, and its promoter contains a W-box palindrome with two reversely oriented TGAC repeats, which are the proposed binding sites of WRKY Cited by: The Human Factor is not, in my opinion, one of the great Graham Greene novels, but it is a good one, written when he was in his seventies, drawing (like John le Carré) on his experience working for British counter-intelligence, and as with le Carré, part of his explicit attempt to reflect what it was really like to work for the agency/5.

In genetics, a promoter is a sequence of DNA to which proteins bind that initiate transcription of a single RNA from the DNA downstream of it. This RNA may encode a protein, or can have a function in and of itself, such as tRNA, mRNA, or ers are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense.

GLI is the prototype for the Gli-Kruppel gene family characterized by a consensus C 2-H 2 zinc finger domain and is believed to function as a transcription activator in the vertebrate Sonic hedgehog-Patched signal transduction pathway. Understanding GLI gene regulation may be of importance to understanding causes of human birth defects and by: In animals, transcription by RNA polymerase II initiates bidirectionally from gene promoters to produce pre-mRNAs on the forward strand and promoter upstream transcripts (PROMPTs) on the reverse strand.

PROMPTs are degraded by the nuclear exosome. Previous studies based on nascent RNA approaches concluded that Arabidopsis thaliana does not produce PROMPTs.

The Human Factor is a British thriller film directed and produced by Otto Preminger and starring Richard Attenborough, Nicol Williamson, Derek Jacobi and John is based on the novel The Human Factor by Graham Greene, with the screenplay written by Tom Stoppard.

[dead link] It examines British espionage, and the West's relationship with apartheid Based on: The Human Factor, by Graham Greene. In the present study, we have cloned the human neurotensin receptor (NTR) gene, determined its structure, demonstrated that its promoter is functional in transfection experiments, and identified the start site of transcription and a tetranucleotide repeat polymorphism that locates at less than 3 kilobase pairs from the by: In this report, the organization of the human secretin receptor (hSR) gene was characterized by overlapping genomic phage clones.

The hSR gene consists of 13 exons and 12 introns with all the splice donor and acceptor sites conforming to the canonical GT/AG by: @article{osti_, title = {Molecular analysis of the human SLC13A4 sulfate transporter gene promoter}, author = {Jefferis, J.

and Rakoczy, J. and School of Biomedical Sciences, University of Queensland, St. Lucia, Queensland and Translational Research Institute, Woolloongabba, Queensland and Simmons, D.

and Dawson, P.A., E-mail:. @article{osti_, title = {Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF)}, author = {Mitchell, R and Bacher, M and Bernhagen, J}, abstractNote = {An emerging body of data indicates that the protein mediator described originally as macrophage migration inhibitory factor (MIF) exerts a central and wide ranging role in host Cited by: "Characterization of a Promoter Rearrangement and a Second Promoter in the Human C-myb Proto-oncogene" has been approved by her committee as satisfactory completion of the dissertation required for the degree of Doctor of Philosophy.

estin, M.D. Director of Dissertation William Dewey, Ph.D. Dean, Scho of Basic Health SciencesAuthor: Sarah Margaret Jacobs.

T1 - Promoter cloning and characterization of the human programmed cell death protein 4 (pdcd4) gene. T2 - Evidence for ZBP and Sp-binding motifs as essential Pdcd4 regulators.

AU - Leupold, Jörg Hendrik. AU - Asangani, Irfan Ahmed. AU - Mudduluru, Giridhar. AU - Allgayer, Heike. PY - /6/1. Y1 - /6/1Cited by: The WRKY transcription factor PuWRKY31 was also expressed more highly in BNG fruit than in NG fruit, and we found that PuWRKY31 bound to the PuSWEET15 promoter and induced its transcription.

The histone acetylation level of the PuWRKY31 promoter was higher in BNG fruit, suggesting a mechanism by which Suc levels can be elevated.

The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent transcription by nucleating pre-initiation complex (PIC) assembly at the.'In the last 30 years of his career', writes Sheldon, 'there are only two books which seem worthy of comparison with his best work': The Honorary Consul () and The Human Factor ().Author: Guardian Staff.The Human Factor by Graham Greene 7, ratings, average rating, reviews The Human Factor Quotes Showing of 10 “Hate is an Cited by: